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High Temporal Resolution Dual-source Photon-counting CT for Coronary Artery Disease: Initial Multicenter Clinical Experience

by Martin Soschynski, Florian Hagen, Stefan Baumann, Muhammad Taha Hagar, Jakob Weiss, Tobias Krauß, Christopher L. Schlett, Constantin von Zur Mühlen, Fabian Bamberg, Konstantin Nikolaou, Simon Greulich, Matthias F. Froelich, Philipp Riffel, Daniel Overhoff, Theano Papavassiliu, Stefan Schönberg, Sebastian Faby, Stefan Ulzheimer, Isabelle Jessica Veronika Ayx, Patrick Krumm · 2022

ISBN:  Unavailable

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Abstract: The aim of this paper is to evaluate the diagnostic image quality of spectral dual-source photon-counting detector coronary computed tomography angiography (PCD-CCTA) for coronary artery disease in a multicenter study. The image quality (IQ), assessability, contrast-to-noise ratio (CNR), Agatston score, and radiation exposure were measured. Stenoses were quantified and compared with invasive coronary angiography, if available. A total of 92 subjects (65% male, age 58 ± 14 years) were analyzed. The prevalence of significant coronary artery disease (CAD) (stenosis ≥ 50%) was 17% of all patients, the range of the Agatston score was 0-2965 (interquartile range (IQR) 0-135). The IQ was very good (one, IQR one-two), the CNR was very high (20 ± 10), and 5% of the segments were rated non-diagnostic. The IQ and assessability were higher in proximal coronary segments (p