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Background and Aims: Interhospital transfers (IHT) for mechanical thrombectomy (MT) are essential for stroke patients with large vessel occlusion (LVO) to access the best treatment in high quality centers. IHT is a demanding process which needs to be continuously evaluated, along with its impact on the outcome of patients.Method: Retrospective study of all ischemic stroke patients treated with MT after direct admission (DA) in a Stroke Center, or admitted in a Stroke Center after IHT from 2 referring hospitals for MT, between Jan/2015 and Jul/2017. DA and IHT groups were compared.Results: 238 patients were included (DA=101, IHT=137), median age=74 (IQR=62-81), 51.7% of female sex, median NIHSS=17 (IQR=13-20), median ASPECTS=9 (IQR=8-10). The most frequent location of occlusion was isolated M1 (48.7%). Among 137 IHT patients, MT was not performed in 31 (22.6%). Time to recanalization was 251.5min (IQR=183-302) in DA patients, and 355min in IHT patients (p