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BackgroundIntracerebral hemorrhage (ICH) is the second most common cause of stroke. Early ICH imaging and diagnostics (e.g., blood pressure, coagulation status) is prognostically crucial. However, only limited data is available on ultra-early hemorrhage growth within the first 60 minutes after symptom onset (u201cgolden houru201d).MethodsWe prospectively collected data on ICH imaging using two registries, the Berlin Mobile Stroke Unit (MSU) registry and B-SPATIAL (clinicaltrials.gov, NCT03027453). We identified 60 patients receiving golden hour imaging: 35 patients with prehospital CT scan aboard the MSU (43.2% of 81 patients), and 25 patients with CT or MR imaging at hospital arrival after EMS transport (14.4% of 174 patients). Hemorrhages were measured using ABC/2 formula.ResultsUnivariate comparison of MSU versus EMS group are shown in Table 1. A logistic regression analysis of functional outcome adjusted for GCS severity revealed no significant difference between both groups. ConclusionWe could show that MSU intervention compared to usual EMS transport, especially in the very early period after ICH, did not raise any safety concerns. Prospective prehospital studies investigating the ultra-early hematoma growth will be carried out using repetitive imaging.