ISBN:  Unavailable

Category: Unavailable

Page count: 264

"Our understanding of the molecular events that occur when surgace receptors are engaged by their ligands has increased greatly in recent years. As signaling pathways have been defined, it has become clear that rather that being organized in a linear fashion, receptor-initiated second messenger cascases intersect at many points within the cell. Work in immune cells investigating the molecular interplay between immunoreceptors and integrins demonstrates well this complexity of signaling. This volume of Immunological Reviews includes articles by leading investigators interested in antigen receptors, integrins or both and provides new insights into how signaling events are coordinated as immune cells develop and respond to pathogenic challenges."--Cover