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Autotoxic Antibiotic Production by a Marine Chromobacterium

by R. J. Anderson ยท 1974

ISBN:  Unavailable

Category: Unavailable

Page count: 5

An antibiotic-producing Chromobacter was isolated from a sea-water sample from the North Pacific Gyre. The bacterium produces 3 bromine-containing metabolites: tetrabromopyrrole, 2-(2'-hydroxy-3', 5'-dibromophenyl)-3, 4, 5-tribromopyrrole, and hexabromo-2, 2'-bipyrrole. It also synthesizes n-propyl 4-hydroxybenzoate and 4-hydroxybenzaldehyde. Some of these compounds were shown to be responsible for autoinhibition of the Chromobacterium itself, as well as for antibiotic action against other kinds of bacteria.