Inhale. Exhale. Repeat. The first thing you do is inhale. The last thing you do is exhale. But what if you fear your own breath? You know that it is limited. There are only so many repetitions you get. But there's a catch. You don't know how many. It is impossible to know. Nobody has ever come back to tell. Except Vivian has. Vivian has been confusing "to breathe" with "to be alive" forever. She has never risked anything in order to keep her safety and it has cost her her life. Then, miraculously, she receives a second chance. What happens when she finally decides to live up to her potential?

This book discusses the foundations of social and environmental accounting and highlights local differences in countries like Italy and Bulgaria. It also describes the institutional environment, which affects the development and application of environmental accounting and reporting, as a basis for evaluating current achievements and the future steps that need to be taken to develop and spread environmental accounting. The book is unique in presenting exemplary cases from different emerging and developed countries. It is a valuable resource for theorists in the field, practitioners in companies, as well as investors and other stakeholders. Moreover, it provides students with the necessary theoretical constructs, empirical studies as well as practical and managerial tools to allow for a quick orientation in the methodology, techniques and selected practices used in environmental accounting and reporting.

In Anne Baldo’s Morse Code for Romantics, patterns of life emerge—and break—in relationships both requited and otherwise. A restaurateur orchestrates a devious punishment for his wife’s lover. A desperate mother searches for her missing daughter, a modern-day Persephone who was lured away by a sinister boyfriend. An islander falls under the spell of a visiting researcher, whose insidious smiles and natural sangfroid mirror the serpent-like sea monster he hunts. These wistful, darkly surreal stories, set in Southern Ontario, suggest that maternal instinct is not just a chemical lie but something bloody and painful; that one person’s clouds can rain on generations; and that true loneliness can be as clear as code written on a face, and as ominous as a dark, monstrous shape lurking beneath the surface.

This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters. It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of the world's 100 biggest selling drugs. Recombinant proteins dominate the growing list of the more than 200 approved biotherapeutic agents with targeted antibodies, fusion proteins and receptors; cytokines; hormones; enzymes; proteins involved in blood-clotting, homeostasis and thrombosis; vaccines; botulinum neurotoxins; and, more recently, biosimilar preparations, comprising the majority of approved biologics. Written with clinicians, other health care professionals, and researchers in mind, Safety of Biologics Therapy examines, in a single volume, the full range of issues surrounding the safety of approved biologic therapies. A good understanding of the risks and safety issues of modern biologics therapy is increasingly being demanded of all those connected with their development, handling, prescribing, administration and subsequent patient management. In addition to being of great value to clinicians in all branches of medicine, and to nurses, pharmacists and researchers, this book will prove invaluable for students taking undergraduate and graduate courses in the above disciplines and in the biomedical sciences.

A distinguishing feature of Shakespeare’s later histories is the prominent role he assigns to the need to forget. This book explore the ways in which Shakespeare expanded the role of forgetting in histories from King John to Henry V, as England contended with what were perceived to be traumatic breaks in its history and in the fashioning of a sense of nationhood. For plays ostensibly designed to recover the past and make it available to the present, they devote remarkable attention to the ways in which states and individuals alike passively neglect or actively suppress the past and rewrite history. Two broad and related historical developments caused remembering and forgetting to occupy increasingly prominent and equivocal positions in Shakespeare’s history plays: an emergent nationalism and the Protestant Reformation. A growth in England’s sense of national identity, constructed largely in opposition to international Catholicism, caused historical memory to appear a threat as well as a support to the sense of unity. The Reformation caused many Elizabethans to experience a rupture between their present and their Catholic past, a condition that is reflected repeatedly in the history plays, where the desire to forget becomes implicated with traumatic loss. Both of these historical shifts resulted in considerable fluidity and uncertainty in the values attached to historical memory and forgetting. Shakespeare’s histories, in short, become increasingly equivocal about the value of their own acts of recovery and recollection.

"Learn how to give your journal or planner a fun, artsy vibe with a variety of doodles that encourage your personality to shine through. This collection of more than 200 hand-drawn motifs includes a wide range of themes to suit your needs, along with practice pages and step-by-step instruction"--Back cover.

This book is dedicated to my mother, Carmela Di Leone, who taught me how to cook, my husband Paul for being my sweet guinea pig and for my children, Liana and Paul who enjoyed my cooking.

Luca Del Baldo's Visionary Academy of Ocular Mentality is an extraordinary testament in the recent history of visual studies. It brings together a group of outstanding scholars who have devoted their lives to art history, philosophy, history, ethnology, focussing predominantly on questions of human perception and imagination. Working from photographs provided by the scholars, Luca del Baldo painted his series of 96 portraits reproduced in this book. The portraits are accompanied by texts written by the persons portrayed, in response to their portrayal, and as an exchange: the artist gifted the original painting to the portrayed person, and the portrayed gifted her or his response. "The result is a unique and profound conversation between image and text focussed on the enigma of the human face in all its mediations." (W.J.T. Mitchell)

The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy that have recently experienced explosive growth: biological therapies and new targeted chemotherapies. Other new and expanded chapters address antimicrobials; drugs used in anesthesia and surgery; opioids; non-targeted anti-cancer drugs; vaccines; and newly understood reaction mechanisms. This new edition includes photographs of a wide variety of cutaneous manifestations that will be of use to other clinicians as well as allergists and dermatologists. In addition to its wide clinical emphasis, the book’s mechanistic and structure-activity detail will provide valuable background for researchers and investigators in universities, medical research institutes, drug companies, and regulatory agencies. The second edition of Drug Allergy is an essential reference for practitioners across the medical disciplines from specialist clinicians, surgeons, GPs, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences.

Performing Shakespearean Appropriations explores the production and consumption of Shakespeare in acts of adaptation and appropriation across time periods and through a range of performance topics. The ten essays, moving from the seventeenth to the twenty-first century, address uses of Shakespeare in the novel, television, cinema, and digital media. Drawing on Christy Desmet's work, several contributors figure appropriation as a posthumanist enterprise that engages with electronic Shakespeare by dismantling, reassembling, and recreating Shakespearean texts in and for digital platforms. The collection thus looks at media and performance technologies diachronically in its focus on Shakespeare’s afterlives. Contributors also construe the notion of “performance” broadly to include performances of selves, of communities, of agencies, and of authenticity—either Shakespeare’s, or the user’s, or both. The essays examine both specific performances and larger trends across media, and they consider a full range of modes: from formal and professional to casual and amateur; from the fixed and traditional to the ephemeral, the itinerant, and the irreverent.