The results of the study indicate that I. resinosum as a producer of laccase and Mn-peroxidase is a promising species for decolorization of textile dyes and dyebaths when used in combination with redox mediators.

In presented work the Galactoglucomannans (GGMs) isolated from process waters in thermomechanical pulp production were chemically modified to increase their haemocompatibility. Therefore GGMs were adsorbed onto poly (ethylene terephtalate) (PET) which is the most used polymer in vascular surgery to increase its biocompatibility. The adsorption was monitored by Quartz Crystal Microbalance with Dissipation unit (QCM-D). Adsorption of GGMs was studied using different anchoring substances; the influence of electrolytes was studied and finally biocompatibility of surfaces were characterised. By measuring activated partial thromboplastine time (APTT), the antithrombogenicity of GGMs and their derivatives was characterized. Blood proteins Fibrinogen and Albumin were adsorbed onto tested surfaces using QCM-D and thereafter surfaces were characterised by AFM imaging. In this work for the first time QCM-D was used for haemocompatibility testing of polymer surfaces in a physiological environment. The GGMs sulphating was confirmed by FTIR and NMR spectroscopy and with ICP-MS. APTT of sulphated products increased significantly showing better anticoagulant properties as non-treated GGMs. Sulphated GGM?s adsorbed on the model and real PET surfaces decreased the surface hydrophobicity and their anticoagulant properties were similar to commercially available anticoagulants such as Heparin and Dextran sulphate. The work presented suggests that galactoglucomannans derived from softwood could be promising new material for biomedical application and its sulphated products could be novel anticoagulants from non-mammalian source.