Instilling good prescribing habits in young doctors is essential for the benefit of patients and to preserve the value of the antibiotic revolution that altered medical practice in the second half of the twentieth century. These concerns underlie the approach taken in the new edition of this successful book. The text provides a comprehensive and up-to-date account of the principles of antimicrobial chemotherapy as an aid to informed, rational prescribing. Care is taken to address all aspects of antimicrobial drug use, including those specific to developed and developing countries of the world. The authors are international experts with a long standing interest in the role of education as a means of promoting an understanding of the benefits and limitations of antimicrobial chemotherapy in physicians, surgeons and other health care workers. The book offers a structured approach to the subject in four themed sections, each of several chapters. A historical introduction is followed by a section outlining the basic properties of antibacterial, antifungal, antiparasitic and antiviral (including antiretroviral) drugs.The next section explains the various facets of antimicrobial drug resistance - which threatens to undermine the continued efficacy of antimicrobial agents - and effective ways of countering the threat. Therapeutic use is covered in two sections: one introduces readers to the general principles that inform the rational prescribing of antimicrobial drugs; the second deals with practicalities of the use of antimicrobial agents in specific clinical conditions. The book ends with a description of the ways in which drugs are developed and marketed. There are extensive recommendations for further reading.

We know that Attention Deficit Disorder makes it tough for children to focus in school. But what happens when those kids grow up? How can they make the transition to a successful professional life? And how can newly diagnosed adults meet the challenges of the workplace? David Greenwood, an ADD sufferer who now works as a well-respected PR consultant, answers the question for anyone who wants to thrive with ADD or ADHD—not just survive! Learn how to: Identify the major features of Attention Deficit Disorder and become aware of how they affect aspects of adult life, particularly in the office Tailor a career to minimize the effects of those symptoms Highlight the positive characteristics of Attention Deficit Disorder, such as hyper-focusing and creativity, and leverage them to achieve professional success Overcoming Distractions includes plenty of case studies, testimonials from ADD/ADHD specialists, and numerous action plans for making Attention Deficit Disorder work for you.

Between 1935 and 1944 the field of microbiology, and by implication medicine as a whole, underwent dramatic advancement. The discovery of the extraordinary antibacterial properties of sulphonamides, penicillin, and streptomycin triggered a frantic hunt for more antimicrobial drugs that was to yield an abundant harvest in a very short space of time. By the early 1960s more than 50 antibacterial agents were available to the prescribing physician and, largely by a process of chemical modification of existing compounds, that number has more than tripled today. We have become so used to the ready availability of these relatively safe and highly effective 'miracle drugs' that it is now hard to grasp how they transformed the treatment of infection. This book documents the progress made from the first tentative search for an elusive 'chemotherapy' of infection in the early days of the twentieth century, to the development of effective antiviral agents for the management of HIV as the millennium drew to a close. It also offers a celebration of the individuals and groups that made this miracle happen, as well as examining the inexorable rise of the global pharmaceutical industry, and, most intriguingly, the essential input of luck. Infection still maintains a high profile in both medicine and the media, with the current threats of 'superbugs' such as MRSA acquired in hospital, and a potential resistance to antibiotics. This book tracks the history of antimicrobial drugs, a remarkable medical triumph that has provided doctors with an amazing armoury of safe and effective drugs that ensure that reversion to the helpless state of the fight against infection witnessed in the early 1900s is extremely unlikely. This timely compendium acknowledges the agents that have surely led to the relief of more human and animal suffering than any other class of drugs in the history of medical endeavour.

Medical microbiology concerns the nature, distribution and activities of microbes and how they impact on health and wellbeing, most particularly as agents of infection. Infections remain a major global cause of mortality and in most hospitals around one in ten of those admitted will suffer from an infection acquired during their stay. The evolution of microbes presents a massive challenge to modern medicine and public health. The constant changes in viruses such as influenza, HIV, tuberculosis, malaria and SARS demand vigilance and insight into the underlying process. Building on the huge success of previous editions, Medical Microbiology 18/e will inform and inspire a new generation of readers. Now fully revised and updated, initial sections cover the basic biology of microbes, infection and immunity and are followed by a systematic review of infective agents, their associated diseases and their control. A final integrating section addresses the essential principles of diagnosis, treatment and management. An unrivalled collection of international contributors continues to ensure the relevance of the book worldwide and complementary access to the complete online version on Student Consult further enhances the learning experience. Medical Microbiology is explicitly geared to clinical practice and is an ideal textbook for medical and biomedical students and specialist trainees. It will also prove invaluable to medical laboratory scientists and all other busy professionals who require a clear, current and most trusted guide to this fascinating field.

The Roman emperor Julian is a figure of ongoing interest and the subject of David Neal Greenwood's Julian and Christianity. This unique examination of Julian as the last pagan emperor and anti-Christian polemicist revolves around his drive and status as a ruler. Greenwood adeptly outlines the dramatic impact of Julian's short-lived regime on the course of history, with a particular emphasis on his relationship with Christianity. Julian has experienced a wide-ranging reception throughout history, shaped by both adulation and vitriol, along with controversies and rumors that question his sanity and passive ruling. His connections to Christianity, however, are rooted in his regime's open hostility, which Greenwood shows is outlined explicitly in Oration 7: To the Cynic Heracleios. Greenwood's close reading of Oration 7 highlights not only Julian's extensive anti-Christian religious program and decided rejection of Christianity but also his brilliant, calculated use of that same religion. As Greenwood emphasizes in Julian and Christianity, these attributes were inextricably tied to Julian's relationship with Christianity—and how he appropriated certain theological elements from the religion for his own religious framework, from texts to deities. Through his nuanced, detailed readings of Julian's writings, Greenwood brings together ancient history, Neoplatonist philosophy, and patristic theology to create an exceptional and thoughtful biography of the great Roman leader. As a result, Julian and Christianity is a deeply immersive look at Julian's life, one that considers his multifaceted rule and the deliberate maneuvers he made on behalf of political ascendancy.

Quality management is essential for facilitating the competitiveness of modern day commercial organisations. Excellence in quality management is a requisite for construction organisations who seek to remain competitive and successful. The challenges presented by competitive construction markets and large projects that are dynamic and complex necessitate the adoption and application of quality management approaches. This new edition of Construction Quality Management provides a comprehensive evaluation of quality management systems and tools. Their effectiveness in achieving project objectives is explored, as well as applications in corporate performance enhancement. Both the strategic and operational dimensions of quality assurance are addressed by focusing on providing models of best practice. The reader is supported throughout by concise and clear explanations and with self-assessment questions. Practical case study examples show how various evaluative-based quality management systems and tools have been applied. Subjects covered include: business objectives – the stakeholder satisfaction methodology organisational culture and Health and Safety quality philosophy evaluation of organisational performance continuous quality improvement and development of a learning organisation. New chapters consider the influence of Building Information Modelling (BIM) on quality management. The text should be of interest to construction industry senior managers, practicing professionals and academics. It is also an essential resource for undergraduate and postgraduate students of construction management, project management and business management courses.

David Greenwood explores how works of art, and especially landscape paintings, can trigger awareness of the transcendental, open paths to religious and spiritual experience, and offer artistic windows into God. He examines the interconnections between art history, spirituality, philosophy, mysticism and theology.