· 2016
For poet Mary Elizabeth Winn, the most profound issues revolved around relationships, and her poems reflect the impact these had on her life, as well as how she impacted others. Wave of the Day: Collected Poems describes childhood, family, children, places lived in and traveled to with an abiding love for nature, relationships, and a faith that can both question and guide throughout a long life. Quiet and soft-spoken, these poems reveal a reflective and deep-thinking woman. We are privileged to enter Mary Elizabeth Winn's now distant yet still timely world of childhood, womanhood, and her surprising life as faithful friend and lover.
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Raising the next generation of Christ-followers may be one of the most difficult assignments God calls you to. Helping your child become a person dedicated to Kingdom purposes can seem daunting. But there are simple steps you can start taking today towards creating a home of everyday ministry. Tracie Moss and Elizabeth Winn have helped hundreds of women with the challenges of raising children focused on seeking the Father's heart and ministering to those around them. In God's Heart for Your Home, they share how you can: * Create an atmosphere of faith and trust * Foster an environment of prayer * Develop healthy communication skills * Encourage your child's God given uniqueness * Establish a heart for others as a family Tracie and Elizabeth blend biblical principles with practical examples from their own lives and some of those they have touched through their Living Well Ministry. They share truths, tips and tools, and offer reflection questions for individual or group study. Whether you're just starting your parenting journey or are much further along, whether you have children at home or grandchildren who come to visit, it's never too late to create a home environment of ministry. Join Tracie and Elizabeth as they explore God's Heart for Your Home.
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· 2011
Microarray-based gene expression profiling is a frequently utilized tool in the search for disease-specific molecular patterns and the development of clinically relevant panels of biomarkers. Although advances in high-throughput gene expression technology make for more reliable and interpretable studies, investigations of living humans are often limited by tissue accessibility. This is especially true for neural-based illnesses, where studies rely heavily on post-mortem brain tissue. As a result, medical researchers have focused on blood, a more easily accessible and clinically obtainable tissue. In this work I explore : 1.) the technical aspects associated with assessing peripheral whole blood gene expression via microarray; and 2.) the biological significance of blood-based gene expression patterns with respect to brain-based gene expression patterns and behavioral phenotypes in mice and humans. I describe the effects of globin reduction on blood-based gene expression in mice by comparing gene expression patterns before and after globin reduction of mouse whole blood (Chapter 2). Globin reduction was found to improve the ability to detect low abundance, biologically relevant genes. I also evaluated globin reduction in the context of human blood and two Illumina gene expression assays : (i) the IVT-based direct hybridization assay; and (ii) the WG-DASL assay (Chapter 4). As in mice, I was able to recapitulate the known benefits of globin reduction in both assays, while WG-DASL appeared to be more sensitive compared to IVT. Lastly, I characterized the correlations between blood gene expression levels and behavioral phenotypes and compared blood gene expression-trait correlations with brain gene expression-trait correlations in respect to neuropsychiatric phenotypes in mice (Chapter 3) and autism in humans (Chapter 5). In both mice and humans, blood was only able to capture a small portion of the associations identified in the brain on an individual gene level. At a pathway level, blood was able to capture a larger portion of the associated brain pathways in humans as compared to mice. I conclude blood gene expression, although it may capture a small portion of the expression patterns associated with 'primary' neural insults, is more likely to capture variation due to 'secondary' perturbations or other biological and environmental insults.
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· 2020
Two women who love the same man. One has held his heart since conception, the other since marriage. One is asked to completely let go and hand off his heart to the other. The other is asked to understand the pain and emotion that goes into this hand-off and receive his heart with grace. Some have done it well....others have not. The Hand-Off speaks truth to both women and ends with speaking to the man in the middle of these two powerful women in his life. No matter where you sit right now in this wonderful, complicated, powerful, sometimes heart-wrenching, sometimes maddening, relationship, there is hope for a closer connection and healing from any pain of the past. Elizabeth Winn is an author and speaker whose heart is helping people find health in the most important relationships in life. She is co-founder of Living Well Ministry, which offers engaging and transformational teaching on a wide variety of subjects. She believes many women in today's society live in crisis mode. The plate of our lives overflow with duties and responsibilities that pull us in multiple directions. We spend our days full of activity, yet miss the key ingredient of life - joy. Elizabeth's goal is to offer hope and practical help to women encouraging them to live their best life. She and her husband, Sean, call Kansas City home. She is also a mother to Taylor and Elin, a mother-in-law to Madeline and a Grammy to Penny.
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