What goes on in our head when we have a thought? Why do the physical events that occur inside a fistful of gelatinous tissue give rise to the world of conscious experience? In The Universe of Consciousness , Gerald Edelman and Giulio Tononi present for the first time a full-scale theory of consciousness based on direct observation of the human brain in action. Their pioneering work, presented here in an elegant style, challenges much of the conventional wisdom about consciousness. The Universe of Consciousness has enormous implications for our understanding of language, thought, emotion, and mental illness.

How does the firing of neurons give rise to subjective sensations, thoughts, and emotions? How can the disparate domains of mind and body be reconciled? The quest for a scientifically based understanding of consciousness has attracted study and speculation across the ages. In this direct and non-technical discussion of consciousness, Dr. Gerald M. Edelman draws on a lifetime of scientific inquiry into the workings of the brain to formulate answers to the mind-body questions that intrigue every thinking person. Concise and understandable, the book explains pertinent findings of modern neuroscience and describes how consciousness arises in complex brains. Edelman explores the relation of consciousness to causation, to evolution, to the development of the self, and to the origins of feelings, learning, and memory. His analysis of the brain activities underlying consciousness is based on recent remarkable advances in biochemistry, immunology, medical imaging, neuroscience, and evolutionary biology, yet the implications of his book extend farther-beyond the worlds of science and medicine into virtually every area of human inquiry.

In this, his first book aimed at the general reader, Gerald Edelman describes how consciousness arises in complex brains and how it is related to evolution, to the development of the self, and to the origins of feelings, learning, and memory. Edelman's theories offer a solution to the mind-body problem. An understanding of the workings of consciousness in scientific terms would be of enormous value in all areas of science, in medicine and psychiatry, and in the humanities.

One of the nation's leading neuroscientists presents a radically new view of the function of the brain and the nervous system. Its central idea is that the nervous system in each individual operates as a selective system resembling natural selection in evolution, but operating by different mechanisms. This far-ranging theory of brain functions is bound to stimulate renewed discussion of such philosophical issues as the mind-body problem, the origins of knowledge and the perceptual bases of language. Notes and Index.

We are on the verge of a revolution in neuroscience as significant as the Galilean revolution in physics or the Darwinian revolution in biology. Nobel laureate Gerald M. Edelman takes issue with the many current cognitive and behavioral approaches to the brain that leave biology out of the picture, and argues that the workings of the brain more closely resemble the living ecology of a jungle than they do the activities of a computer. Some startling conclusions emerge from these ideas: individuality is necessarily at the very center of what it means to have a mind, no creature is born value-free, and no physical theory of the universe can claim to be a ”theory of everything” without including an account of how the brain gives rise to the mind. There is no greater scientific challenge than understanding the brain. Bright Air, Brilliant Fire is a book that provides a window on that understanding.

Burgeoning advances in brain science are opening up new perspectives on how we acquire knowledge. Indeed, it is now possible to explore consciousness - the very centre of human concern - by scientific means. In this illuminating book, Dr. Gerald M. Edelman offers a new theory of knowledge based on striking scientific findings about how the brain works. And he addresses the related compelling question: does the latest research imply that all knowledge can be reduced to scientific description? Edelman's brain-based approach to knowledge has rich implications for our understanding of creativity, of the normal and abnormal functioning of the brain, and of the connections among the different ways we have of knowing. While the gulf between science and the humanities and their respective views of the world has seemed enormous in the past, the author shows that their differences can be dissolved by considering their origins in brain functions. He foresees a day when brain-based devices will be conscious, and he reflects on this and other fascinating ideas about how we come to know the world and ourselves.

Written by Nobel Prize laureate Gerald M. Edelman, this book develops a remarkable theory of consciousness that integrates findings from the recent explosive growth of the neurosciences with current knowledge of anatomy, cell biology, and psychology. In constructing a detailed model of how we become aware of our own existence, Edelman provides an outlook that may prompt a fundamental revision in the way linguists view language, physicians classify mental disease, and philosophers look at the mind-body problem. Notes and Index.

One of the vastly exciting areas in modern science involves the study of the brain. Recent research focuses not only on how the brain works but how it is related to what we normally call the mind, and throws new light on human behavior. Progress has been made in researching all that relates to interior man, why he thinks and feels as he does, what values he chooses to adopt, and what practices to scorn. All of these attributes make us human and help to explain art, philosophy, and religions. Motion, sight, and memory, as well as emotions and the sentiments common to humans, are all given new meaning by what we have learned about the brain. In an introductory essay, Vernon B. Mountcastle traces the progress made in brain science during this century. Gerald M. Edelman touches upon features of the brain that challenge the picture of the brain as a machine. Semir Zeki discusses artists and artistic expression as an extension of the function of the brain. Richard S. J. Frackowiak probes the functional architecture of the brain. Mark F. Bear and Leon N Cooper explore whether complex neural systems can be illuminated by theoretical structures. Jean-Pierre Changeux sheds light on the knowledge gained in recent years concerning the neurobiology and pharmacology of drug action and addiction. Alexander A. Borbuly and Giulio Tononi ponder the quest for the essence of sleep, illuminating its complex dynamic process. George L. Gabor Miklos examines variations in neuroanatomies and sensory systems between individuals of the same species as well as variations across the evolutionary spectrum. Emilio Bizzi and Ferdinando A. Mussa-Ivaldi explain how scientists have approached the study of movement, the problems encountered, and the solutions proposed. Marcel Kinsbourne explores the unity and diversity in the human brain. In the concluding essay, Andy Clark points to recent work in neuroscience, robotics, and psychology that stresses the unexpected intimacy of brain, body, and world, supporting his belief that the mind is best understood as a brain at home in its proper bodily cultural and environmental niche. The breadth and scope of subjects covered in this volume attest to the extraordinary progress taking place in the study of the brain. This brilliant collection of essays by those at the forefront of research in this area will be of interest to all those interested in human behavior. Gerald M. Edelman is director of the Neurosciences Institute and chairman of the Department of Neurobiology at the Scripps Research Institute. Jean-Pierre Changeux is professor at the Collbge de France and the Institute Pasteur.

A proposal by two eminent biological scientists for a mechanism whereby mind becomes manifest from the operations of brain tissue. This significant contribution to neuroscience consists of two papers, the first by Mountcastle an, the second by Edelman. Between them, they examine from different but complementary directions the relationships that connect the higher brain—memory, learning, perception, thinking—with what goes on at the most basic levels of neural activity, with particular stress on the role of local neuronal circuits.Edelman's major hypothesis is that "the conscious state results from phasic reentrant signaling occurring in parallel processes that involve associations between stored patterns and current sensory or internal input." This selective process occurs by the polling of degenerate primary repertoires of neuronal groups that are formed during embryogenesis and development. Edelman's theory extrapolates to the brain the selectionistic immunological theories for which he was awarded the 1972 Nobel Prize in Physiology or Medicine. Mountcastle's paper reviews what is known about the actual structure of various parts of the neo cortex. He relates the large entities of the neocortex to their component modules—the local neuronal circuits—and shows how the complex interrelationships of such a distributed system can yield dynamic distributed functioning. There are strong conceptual parallels between Mountcastle's idea of cortical columns and their functional subunits and Edelman's concept of populations of neurons functioning as processors in a brain system based on selectional rather than instructional principles. These parallels are traced and put into perspective in Francis Schmitt's Introduction.

What goes on in our heads when we have a thought? With this book, Edelman and Tononi present an empirically-supported full-scale theory of consciousness. They apply all of the resources and insights of modern neuroscience, from the largest computermodels ever constructed to new experiments that detect the changes in brain activity. This pioneering work represents a landmark in our growing understanding of consciousness. Praise for Gerald Edelman: "The new Darwin...His theory is an enrichment of life itself" - Oliver Sacks, The Times