"New, revised edition of the most comprehensive book for bioengineering students and professionals." -- Prové de l'editor.

This short book provides basic information about bioinstrumentation and electric circuit theory. Many biomedical instruments use a transducer or sensor to convert a signal created by the body into an electric signal. Our goal here is to develop expertise in electric circuit theory applied to bioinstrumentation. We begin with a description of variables used in circuit theory, charge, current, voltage, power and energy. Next, Kirchhoff's current and voltage laws are introduced, followed by resistance, simplifications of resistive circuits and voltage and current calculations. Circuit analysis techniques are then presented, followed by inductance and capacitance, and solutions of circuits using the differential equation method. Finally, the operational amplifier and time varying signals are introduced. This lecture is written for a student or researcher or engineer who has completed the first two years of an engineering program (i.e., 3 semesters of calculus and differential equations). A considerable effort has been made to develop the theory in a logical manner—developing special mathematical skills as needed. At the end of the short book is a wide selection of problems, ranging from simple to complex.

There are five different types of eye movements: saccades, smooth pursuit, vestibular ocular eye movements, optokinetic eye movements, and vergence eye movements. The purpose of this book is focused primarily on mathematical models of the horizontal saccadic eye movement system and the smooth pursuit system, rather than on how visual information is processed. A saccade is a fast eye movement used to acquire a target by placing the image of the target on the fovea. Smooth pursuit is a slow eye movement used to track a target as it moves by keeping the target on the fovea. The vestibular ocular movement is used to keep the eyes on a target during brief head movements. The optokinetic eye movement is a combination of saccadic and slow eye movements that keeps a full-field image stable on the retina during sustained head rotation. Each of these movements is a conjugate eye movement, that is, movements of both eyes together driven by a common neural source. A vergence movement is a non-conjugate eye movement allowing the eyes to track targets as they come closer or farther away. In this book, a 2009 version of a state-of-the-art model is presented for horizontal saccades that is 3rd-order and linear, and controlled by a physiologically based time-optimal neural network. The oculomotor plant and saccade generator are the basic elements of the saccadic system. The control of saccades is initiated by the superior colliculus and terminated by the cerebellar fastigial nucleus, and involves a complex neural circuit in the mid brain. This book is the second part of a book series on models of horizontal eye movements. Table of Contents: 2009 Linear Homeomorphic Saccadic Eye Movement Model and Post-Saccade Behavior: Dynamic and Glissadic Overshoot / Neural Network for the Saccade Controller

There are five different types of eye movements: saccades, smooth pursuit, vestibular ocular eye movements, optokinetic eye movements, and vergence eye movements. The purpose of this book is focused primarily on mathematical models of the horizontal saccadic eye movement system and the smooth pursuit system, rather than on how visual information is processed. A saccade is a fast eye movement used to acquire a target by placing the image of the target on the fovea. Smooth pursuit is a slow eye movement used to track a target as it moves by keeping the target on the fovea. The vestibular ocular movement is used to keep the eyes on a target during brief head movements. The optokinetic eye movement is a combination of saccadic and slow eye movements that keeps a full-field image stable on the retina during sustained head rotation. Each of these movements is a conjugate eye movement, that is, movements of both eyes together driven by a common neural source. A vergence movement is a non-conjugate eye movement allowing the eyes to track targets as they come closer or farther away. In this book, early models of saccades and smooth pursuit are presented. The smooth pursuit system allows tracking of a slow moving target to maintain its position on the fovea. Models of the smooth pursuit have been developed using systems control theory, all involving a negative feedback control system that includes a time delay, controller and plant in the forward loop, with unity feedback. The oculomotor plant and saccade generator are the basic elements of the saccadic system. The oculomotor plant consists of three muscle pairs and the eyeball. A number of oculomotor plant models are described here beginning with the Westheimer model published in 1954, and up through our 1995 model involving a 4$^{th}$ order oculomotor plant model. The work presented here is not an exhaustive coverage of the field, but focused on the interests of the author. In Part II, a state-of-art model of the saccade system is presented, including a neural network that controls the system. Table of Contents: Introduction / Smooth Pursuit Models / Early Models of the Horizontal Saccadic Eye Movement System / Velocity and Acceleration Estimation / 1995 Linear Homeomorphic Saccadic Eye Movement Model

Fundamentals of Biomedical Engineering: A First Course is for students taking a first or introductory undergraduate course in biomedical engineering, typically at Sophomore or Junior level. It is written for students who have completed first courses in math, physics and chemistry, who are being introduced to the wide range of inter-connected topics that comprise today’s BME curriculum. Opening with a survey of what BME is, and what biomedical engineers can contribute to the well-being of human life, the book introduces the key mathematical techniques based primarily on static conditions, but through to 1st order differential equations (derivatives and integrals) where necessary. The scope of the book is limited to the needs of a single semester introductory course, covering the basics of signals and signal processing; biological and cellular systems; biomechanics; biomaterials and tissue engineering; biochemistry; bioinstrumentation and medical imaging; and ethics. The book also provides a primer on anatomy and physiology. This text reflects the need for an engineering focused introduction to biomedical engineering and bioengineering and specifically meets ABET requirements for courses to develop in their graduates an understanding of biology and physiology and the capability to apply advanced mathematics (including differential equations and statistics), science, and engineering to solve problems at the interface of engineering and biology. It also directly addresses the need for students to have an ability to make measurements on and interpret data from living systems, and addresses the problems associated with the interaction between living and non-living materials and systems. The book integrates modelling and analysis and is backed up throughout by MATLAB-based examples and exercises. All key concepts and equations are fully defined and provided with worked out derivations and comments to help students connect the math with the physics, and the physics with the biology. The book employs a robust pedagogy to help students and instructors navigate the subject, and is enhanced by accompanying teaching resources including MATLAB tutorials, lecturing slides, BME links and projects, an updated assignment and homework library and a fully worked Instructor’s Manual. Full color illustrations of biological and engineers systems throughout the text help students to really engage with and understand unfamiliar topics and concepts. John Enderle and Joe Bronzino are two of the best known biomedical engineers today, renowned for their encylopedic Introduction to Biomedical Engineering. Their expertise and authority has helped them to create this essential first text, which can be used both as a stand alone text in its own right, or as a precursor to the advanced text. Where students move on to the advanced text at senior or graduate level they will benefit from a logical continuation of style and approach and authority.