The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is being addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.

The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is beeing addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.

Engage with the visual world of disease with this accessible introduction to molecular imaging. This book provides users of all levels with the characterization and measurement of biological processes on a cellular level, functioning within humans, and other living systems. This important new introduction to the field will enable the reader to recognize the major methods, modalities and varied applications of molecular imaging in an efficient and effective way. Featuring techniques from areas such as nuclear medicine, magnetic resonance spectroscopy, optical imaging, and nanotechnology, the book also covers the current movement towards precision medicine thereby driving exceptional hospital care, worldwide. Molecular Imaging provides valuable insight into the properties that improve patient diagnosis. Serving to inform experienced physicians, students, and beginners alike, this convenient introduction is tailored to an individual with the desire to effectively grasp the basic concepts of molecular imaging, under the constraints of a busy professional career.

The current progress in molecular medicine allows the identification of a plethora of new and often human-specific drug targets. An early in vivo validation of specific ligands binding to these targets in humans is needed to assess their potential for targeted imaging and radiotherapy. Radiopharmaceuticals are uniquely suitable for such target validation studies. The purpose of the Ernst Schering Research Foundation Workshop 48 was to offer a forum for an open exchange on the state of the art in the early development of such radiopharmaceuticals. Experts from academia, industry and regulatory authorities provided contributions covering the identification of targets, the necessary preclinical studies on the safety of ligands as well as their validation in human clinical trials.

12 humorvolle und emotionale Geschichten über die Tücken des Reisens, die alltäglichen Absurditäten im Ausland und die wilden Erfahrungen in den Krankenhäusern der Welt.