Environmental pollutants such as lead, mercury, and pesticides interfere with brain development, yet we do not test industrial chemicals for brain toxicity. In this book, Philippe Grandjean argues for the necessity of protecting the brains of future generations and proposes a plan of action to halt what he refers to as chemical brain drain

Today, one out of every six children suffers from some form of neurodevelopmental abnormality. The causes are mostly unknown. Some environmental chemicals are known to cause brain damage and many more are suspected of it, but few have been tested for such effects. Philippe Grandjean provides an authoritative and engaging analysis of how environmental hazards can damage brain development and what we can do about it. The brain's development is uniquely sensitive to toxic chemicals, and even small deficits may negatively impact our academic achievements, economic success, risk of delinquency, and quality of life. Chemicals such as mercury, polychlorinated biphenyls (PCBs), arsenic, and certain pesticides pose an insidious threat to the development of the next generation's brains. When chemicals in the environment affect the development of a child's brain, he or she is at risk for mental retardation, cerebral palsy, autism, ADHD, and a range of learning disabilities and other deficits that will remain for a lifetime. We can halt chemical brain drain and protect the next generation, however, and Grandjean tells us how. First, we need to control all of the 200 industrial chemicals that have already been proven to affect brain functions in adults, as their effects on the developing brain are likely even worse. We must also push for routine testing for brain toxicity, stricter regulation of chemical emissions, and more required disclosure on the part of industries who unleash hazardous chemicals into products and the environment. Decisions can still be made to protect the brains of future generations. -In his crisply written, deeply documented book, Dr. Philippe Grandjean, renowned physician and public health specialist, describes the exquisite vulnerability of the developing human brain to toxic chemicals in the environment, a vulnerability that he ascribes to the brain's almost unimaginable complexity. Today, nearly one in 6 children is born with a neurodevelopmental disorder - a birth defect of the brain. One in 8 has attention deficit disorder. One in 68 is diagnosed with autism spectrum disorder. These rates are far higher than those of a generation ago, and, although they are less publicized, the problems are more prevalent than those caused by thalidomide in the 1960's. The increases are far too rapid to be genetic. They cannot be explained by better diagnosis. How then could they have come to be? Dr. Grandjean has a diagnosis -- the thousands of toxic chemicals that have been released to the environment in the past 40 years with no testing for toxicity. David P. Rall, former Director of the US National Institute of Environmental Health Sciences, once stated that 'If thalidomide had caused a ten-point loss of IQ rather than obvious birth defects of the limbs, it would probably still be on the market'. This is the core message of Dr. Grandjean's 'must read' book.- - Philip J. Landrigan, Dean for Global Health, Ethel H. Wise Professor and Chairman and Director, Children's Environmental Health Center, Mount Sinai School of Medicine

There is increasing evidence that absorption through the skin is a relevant factor in occupational health. This book provides a review of the evidence and possible suggestions for safety practices in the workplace. The opening section outlines the mechanism of percutaneous absorption and the methods used to evaluate its significance. The rest of the book reviews different classes of chemicals with emphasis on those compounds that are considered major skin hazards.

Indsatsen begynder hos de mindste børn og de unge piger, for flere miljøgifte hober sig op i kroppen og går direkte videre til fosteret. Fremtidens kloge hoveder er afhængige af unge kvinders viden og vaner. “Vi har kun én chance for at udvikle en hjerne, og den er i fosterstadiet og de første leveår,” fastslår Philippe Grandjean, der har drevet forskningsprojekter i hele verden for at undersøge miljøets påvirkning af menneskers intelligens og udvikling. Bogen er Philippe Grandjeans personlige og let læste fortælling om disse forsøg og deres resultater. Den skræller lag på lag af årtiers uvidenhed, naivitet og korruption, som har ført til udbredelsen af de farlige miljøgifte. Og den fortæller om en af Danmarks skarpe forskere og hans livslange arbejde i miljøets tjeneste.

On a beaucoup écrit sur la deuxième Guerre mondiale et sur la guerre d'Indochine (1949-1954). Mais très peu sur l'étonnante aventure de l'Indochine dans la deuxième Guerre mondiale (1940-1945). Isolée, soudain, d'une métropole écrasée en juin 1940, l'Indochine française de l'amiral Decoux est restée, après 1942, le seul îlot "blanc" dans le raz de marée nippon d'après Pearl Harbor. Cet "incroyable pari", suivant le mot de L. Bodard, a tenu cinq ans. Pourquoi le 9 mars 1945, Tokyo a-t-il été conduit à balayer l'imperium français? Le 9 mars 1945 a engendré la guerre d'Indochine.

Une analyse détaillée de la pièce de Victor Hugo, au programme de littérature pour le bac 2019-2020 : sa genèse, sa réception et ses caractéristiques littéraires clés. Pour les deux sessions du bac 2019 et 2020, Hernani est au programme de littérature française en terminale L, dans le cadre du domaine d’étude « Lire, écrire, publier ». Ce Profil du bac en propose une analyse approfondie. Il permet notamment de mieux comprendre comment cette pièce de théâtre a constitué un véritable événement littéraire en 1830 et est devenue emblématique du romantisme.

La performance est un concept qui a envahi le monde de la santé à tous les niveaux. Ce concept est cependant difficile à appréhender : la performance comporte de multiples dimensions dont chacune n’éclaire qu’un aspect de la question. En outre, il fait — entre autres — référence à la dimension économique du soin qui n’est pas spontanément ancrée dans le secteur. Une approche globale portant non seulement sur chacune des dimensions, mais également sur le produit de leurs interactions, est nécessaire pour rendre compte du concept. Un éclairage selon les points de vue des différentes parties prenantes du système de santé est également à considérer pour comprendre toute la complexité du déploiement et du pilotage de la performance au niveau macro et microéconomique. Simon Azaïs – Olivier Baly – Marie Boucher – Grégor Bouville – Alice Casagrande – Marie-Claire Chauvancy – Robert H Desmarteau – Céline Dugast – Catherine Dumas – Nadine Durand – Véronique Duveau – Jacques Fresnais – Anne Girault – Gisèle Hoareau – Daniel Jancourt – Yves Joncour – Sfaya Kouidri-Uzan – Emmanuelle Le Roy – Sylvie Lucas – Étienne Minvielle – Christine Moriceau – Roland Muller – Olivier Ovaguimian – Michel Simart – Carole Trempe

First published in 1984: This book is a compilation of research on Organolead Compounds.