These Lecture Notes have been compiled from the material presented by the second author in a lecture series ('Nachdiplomvorlesung') at the Department of Mathematics of the ETH Zurich during the summer term 2002. Concepts of 'self adaptivity' in the numerical solution of differential equations are discussed with emphasis on Galerkin finite element methods. The key issues are a posteriori er ror estimation and automatic mesh adaptation. Besides the traditional approach of energy-norm error control, a new duality-based technique, the Dual Weighted Residual method (or shortly D WR method) for goal-oriented error estimation is discussed in detail. This method aims at economical computation of arbitrary quantities of physical interest by properly adapting the computational mesh. This is typically required in the design cycles of technical applications. For example, the drag coefficient of a body immersed in a viscous flow is computed, then it is minimized by varying certain control parameters, and finally the stability of the resulting flow is investigated by solving an eigenvalue problem. 'Goal-oriented' adaptivity is designed to achieve these tasks with minimal cost. The basics of the DWR method and various of its applications are described in the following survey articles: R. Rannacher [114], Error control in finite element computations. In: Proc. of Summer School Error Control and Adaptivity in Scientific Computing (H. Bulgak and C. Zenger, eds), pp. 247-278. Kluwer Academic Publishers, 1998. M. Braack and R. Rannacher [42], Adaptive finite element methods for low Mach-number flows with chemical reactions.

The interaction of a fluid with a solid body is a widespread phenomenon in nature, occurring at different scales and different applied disciplines. Interestingly enough, even though the mathematical theory of the motion of bodies in a liquid is one of the oldest and most classical problems in fluid mechanics, mathematicians have, only very recently, become interested in a systematic study of the basic problems related to fluid-structure interaction, from both analytical and numerical viewpoints. Fundamental Trends in Fluid-Structure Interaction is a unique collection of important papers written by world-renowned experts aimed at furnishing the highest level of development in several significant areas of fluid-structure interactions. The contributions cover several aspects of this discipline, from mathematical analysis, numerical simulation and modeling viewpoints, including motion of rigid and elastic bodies in a viscous liquid, particulate flow and hemodynamic.

This volume consists of five research articles, each dedicated to a significant topic in the mathematical theory of the Navier-Stokes equations, for compressible and incompressible fluids, and to related questions. All results given here are new and represent a noticeable contribution to the subject. One of the most famous predictions of the Kolmogorov theory of turbulence is the so-called Kolmogorov-obukhov five-thirds law. As is known, this law is heuristic and, to date, there is no rigorous justification. The article of A. Biryuk deals with the Cauchy problem for a multi-dimensional Burgers equation with periodic boundary conditions. Estimates in suitable norms for the corresponding solutions are derived for "large" Reynolds numbers, and their relation with the Kolmogorov-Obukhov law are discussed. Similar estimates are also obtained for the Navier-Stokes equation. In the late sixties J. L. Lions introduced a "perturbation" of the Navier Stokes equations in which he added in the linear momentum equation the hyper dissipative term (-Ll),Bu, f3 ~ 5/4, where Ll is the Laplace operator. This term is referred to as an "artificial" viscosity. Even though it is not physically moti vated, artificial viscosity has proved a useful device in numerical simulations of the Navier-Stokes equations at high Reynolds numbers. The paper of of D. Chae and J. Lee investigates the global well-posedness of a modification of the Navier Stokes equation similar to that introduced by Lions, but where now the original dissipative term -Llu is replaced by (-Ll)O:u, 0 S Ct

This volume consists of six articles, each treating an important topic in the theory ofthe Navier-Stokes equations, at the research level. Some of the articles are mainly expository, putting together, in a unified setting, the results of recent research papers and conference lectures. Several other articles are devoted mainly to new results, but present them within a wider context and with a fuller exposition than is usual for journals. The plan to publish these articles as a book began with the lecture notes for the short courses of G.P. Galdi and R. Rannacher, given at the beginning of the International Workshop on Theoretical and Numerical Fluid Dynamics, held in Vancouver, Canada, July 27 to August 2, 1996. A renewed energy for this project came with the founding of the Journal of Mathematical Fluid Mechanics, by G.P. Galdi, J. Heywood, and R. Rannacher, in 1998. At that time it was decided that this volume should be published in association with the journal, and expanded to include articles by J. Heywood and W. Nagata, J. Heywood and M. Padula, and P. Gervasio, A. Quarteroni and F. Saleri. The original lecture notes were also revised and updated.

This book surveys research results on the physical and mathematical modeling, as well as the numerical simulation of complex fluid and structural mechanical processes occurring in the human blood circulation system. Topics treated include continuum mechanical description; choice of suitable liquid and wall models; mathematical analysis of coupled models; numerical methods for flow simulation; parameter identification and model calibration; fluid-solid interaction; mathematical analysis of piping systems; particle transport in channels and pipes; artificial boundary conditions, and many more. The book was developed from lectures presented by the authors at the Oberwolfach Research Institute (MFO), in Oberwolfach-Walke, Germany, November, 2005.

The articles in this volume summarize the research results obtained in the former SFB 359 "Reactive Flow, Diffusion and Transport" which has been supported by the DFG over the period 1993-2004. The main subjects are physical-chemical processes sharing the difficulty of interacting diffusion, transport and reaction which cannot be considered separately. The modeling and simulation within this book is accompanied by experiments.