Schlaf ist eine oft unterschätzte Grundlage unseres Wohlbefindens. In einer Zeit, in der ständige Erreichbarkeit, Reizüberflutung und Stress unseren Alltag prägen, leidet unser Schlaf jedoch oft. Die Folgen reichen von Tagesmüdigkeit über Konzentrationsprobleme bis hin zu ernsthaften gesundheitlichen Beeinträchtigungen. Die renommierten Schlafforscher und Mediziner Prof. Dr. med. J. Ulrich Sommer und Prof. Dr. med. Clemens Heiser zeigen, dass Schlaf einer der Schlüssel zu einem erfüllten und vitalen Leben ist. Mit fundiertemWissen und ihrer erprobten „Schlafformel nach Heiser & Sommer“ helfen sie dabei, wieder erholsame Nächte zu genießen – von den Grundlagen des Schlafs über die Auswirkungen von Technologien bis hin zu bewährten Methoden zur Bewältigung von Schlafproblemen.

Wenn der Mond aufgeht und die Sterne funkeln, beginnt in vielen Schlafzimmer rund um den Globus ein Konzert der besonderen Art: das Schnarch-Konzert. Aber wie entstehen eigentlich diese Geräusche, die unzählige Bettnachbarinnen und -nachbarn auf der ganzen Welt nachts wachhalten? Und was hilft gegen Schnarchen? Diesen Fragen gehen Prof. Dr. Clemens Heiser und Dr. Sarah Julia Breu in ihrem Ratgeber auf den Grund. Sie erzählen die Geschichte des Schnarchens, zeigen, welche Schnarch-Typen es gibt und gehen auf Ursachen und Behandlungsmöglichkeiten ein – vom Anti-Schnarch- Kissen über bewährte Hausmittel bis hin zu Tipps für genervte Partnerinnen und Partner. Ihre bewährte Anti-Schnarch-Formel hilft dabei, endlich ruhige Nächte zu verbringen.

Abstract: Therapies of head and neck squamous cell carcinoma (HNSCC), particularly irradiation and chemotherapy (C/RT), can affect salivary glands to some extent. Recent studies suggest that point shear wave elastography (pSWE) is well suited for the diagnosis and rating of homogenous damage to parenchymatous organs. The purpose of this study was to assess the value of this sonographic modality as a tool for the evaluation both of salivary gland affection after HNSCC therapy and the effect of a salivary replacement therapy based on liposomes. A total of 69 HNSCC patients were included in this study. All patients had finished cancer treatment and attended regular follow-up. pSWE values of ipsi- and contralateral parotid (PG) and submandibular glands (SMG) were obtained in a standardized manner and compared to those of a healthy control (HC) group. After a two months treatment with a liposomal saliva replacement therapy pSWE quantification was performed again. Ipsi- and contralateral salivary glands suffer under standard HNSCC tumor therapy. Here, the ipsilateral parotid gland (PG) is primarily affected. Therefore, a sequence of manifestation (surgery surgery plus adjuvant C/RT

Abstract: Purpose Selective hypoglossal nerve stimulation has proven to be a successful treatment option in patients with obstructive sleep apnea. The aim of this pilot study was to investigate if there is a cross-innervation of the hypoglossal nerve in humans and if patients with this phenotype show a different response to hypoglossal nerve stimulation compared to those with ipsilateral-only innervation Methods Nineteen patients who previously received a selective hypoglossal nerve stimulation system (Inspire Medical Systems, Golden Valley, USA) were implanted with a nerve integrity system placing electrodes on both sides of the tongue. Tongue motions were recorded one and two months after surgery from transoral and transnasal views. Polysomnography (PSG) was also performed at two months. Electromyogram (EMG) signals and tongue motions after activation were compared with PSG findings. Results Cross-innervation showed significant correlation with bilateral tongue movement and bilateral tongue base opening, which were associated with better PSG outcomes. Conclusion Cross motor innervation of the hypoglossal nerve occurs in approximately 50% of humans, which is associated with a positive effect on PSG outcomes. Bilateral stimulation of the hypoglossal nerve may be a solution for non-responding patients with pronounced collapse at the soft palate during drug-induced sleep endoscopy