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Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an IPSC-Derived 3D Human Brain Model
Xiali Zhong
, Georgina Harris
, Lena Smirnova
, Valentin Zufferey
, Rita de Cássia da Silveira e Sá
, Fabiele Baldino Russo
, Patricia Cristina Baleeiro Beltrao Braga
, Megan Chesnut
, Thomas Hartung
, David Pamies
· 2020
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Advanced Good Cell Culture Practice for Human Primary, Stem Cell-derived and Organoid Models as Well as Microphysiological Systems
David Pamies
, Anna K. Bal-Price
, Christophe Chesné
, Chantra Eskes
, Andras Dinnyes
, Regina Grillari
, Thomas Hartung
, Marcel Leist
, Mardas Daneshian
· 2018
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Human IPSC 3D Brain Model as a Tool to Study Chemical-induced Dopaminergic Neuronal Toxicity
David Pamies
, Daphne Wiersma
, Moriah E. Katt
, Liang Zhao
, Johannes Burtscher
, Georgina Harris
, Lena Smirnova
, Peter C. Searson
, Thomas Hartung
, Helena T. Hogberg
· 2022
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Human IPSC-Derived Model to Study Myelin Disruption
Megan Chesnut
, Hélène Paschoud
, Cendrine Repond
, Lena Smirnova
, Thomas Hartung
, Marie-Gabrielle Zurich
, Helena T. Hogberg
, David Pamies
· 2021
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Microglia Increase Inflammatory Responses in IPSC-Derived Human BrainSpheres
Celina Monteiro Abreu
, Lucio Gama
, Susanne Krasemann
, Megan Chesnut
, Shelly Odwin-DaCosta
, Helena T. Hogberg
, Thomas Hartung
, David Pamies
· 2018
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A Human IPSC-derived 3D Platform Using Primary Brain Cancer Cells to Study Drug Development and Personalized Medicine
Simon Plummer
, Stephanie Wallace
, Graeme Ball
, Roslyn Lloyd
, Paula Schiapparelli
, Alfredo Quinones-Hinojosa
, Thomas Hartung
, David Pamies
· 2019
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Gene-Environment Interactions in Developmental Neurotoxicity: A Case Study of Synergy Between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres
Sergio Modafferi
, Xiali Zhong
, André Kleensang
, Yohei Murata
, Francesca Fagiani
, David Pamies
, Helena T. Hogberg
, Vittorio Calabrese
, Thomas Hartung
, Lena Smirnova
· 2021
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G)×)E Interactions as a Basis for Toxicological Uncertainty
Ilinca Suciu
, David Pamies
, Roberta Peruzzo
, Petra H. Wirtz
, Giorgia Pallocca
, Christof R. Hauck
, Thomas Brunner
, Thomas Hartung
, Ivano Amelio
, Marcel Leist
· 2023
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Toward a 3D Model of Human Brain Development for Studying Gene/environment Interactions
Helena T. Hogberg
, Joseph Bressler
, Kimberly M. Christian
, Georgina Harris
, Georgia Makri
, Cliona O'Driscoll
, David Pamies
, Lena Smirnova
, Zhexing Wen
, Thomas Hartung
· 2013
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Good Cell and Tissue Culture Practice 2.0 (GCCP 2.0): Draft for Stakeholder Discussion and Call for Action
David Pamies
, Marcel Leist
, Sandra Coecke
, Gerard Bowe
, Dave Allen
, Gerhard Gstraunthaler
, Anna Bal-Price
, Francesca Pistollato
, Rob DeVries
, Thomas Hartung
· 2020