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New Approach Methodologies in Human Regulatory Toxicology: Not If, But how and When!
Sebastian Schmeißer
, Andrea Miccoli
, Martin von Bergen
, Elisabet Berggren
, Albert Braeuning
, Wibke Busch
, Christian Desaintes
, Anne Gourmelon
, Thomas Hartung
, Marcel Leist
· 2023
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Recommendation on Test Readiness Criteria for New Approach Methods in Toxicology: Exemplified for Developmental Neurotoxicity
Anna K. Bal-Price
, Helena T. Hogberg
, Kevin M. Crofton
, Mardas Daneshian
, Rex E. FitzGerald
, Ellen Fritsche
, Tuula Heinonen
, Stefanie Klima
, Tanja Waldmann
, Marcel Leist
· 2018
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Optimizing Drug Discovery by Investigative Toxicology: Current and Future Trends
Mario Beilmann
, Harrie Boonen
, Andreas Czich
, Gordon Dear
, Philip Hewitt
, Mardas Daneshian
, Thomas Steger-Hartmann
, Marcel Leist
, Costanza Rovida
· 2019
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Automated Image Processing to Quantify Neurite Growth in Luhmes Human Neuronal Precursor Cells
Dorit Merhof
, Felix Schönenberger
, Nina Stiegler
, Anne-Kathrin Krug
, Thorsten Rieß
, Christiaan Karreman
, Marcel Leist
, Elisa May
· 2012
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Human Embryonic Stem Cell-derived Test Systems for Developmental Neurotoxicity: A Transcriptomics Approach
Anne-Kathrin Krug
, Raivo Kolde
, John Gaspar
· 2013
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Consensus Statement on the Need for Innovation, Transition and Implementation of Developmental Neurotoxicity (DNT) Testing for Regulatory Purposes
Ellen Fritsche
, Philippe Grandjean
, Kevin M. Crofton
, Michael Aschner
, Alan Goldberg
, Tuula Heinonen
, Ellen V. S. Hessel
, Helena T. Hogberg
, Marcel Leist
, Anna Bal-Price
· 2018
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Non-animal Models of Epithelial Barriers (skin, Intestine and Lung) in Research, Industrial Applications and Regulatory Toxicology
Sarah Gordon
· 2015
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Inhibition of Microglial Inflammation by the MLK Inhibitor CEP-1347
Søren Lund
, Peter Porzgen
, Anna-Louise Mortensen
· 2009
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Dynamic Metabolic and Transcriptional Responses of Proteasome-Inhibited Neurons
Ilinca Suciu
, Johannes Delp
, Simon Gutbier
, Anna-Katharina Ückert
, Anna-Sophie Spreng
, Christiaan Karreman
, Falk Schreiber
, Ivana Celardo
, Ivano Amelio
, Marcel Leist
· 2023
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The EU-ToxRisk Method Documentation, Data Processing and Chemical Testing Pipeline for the Regulatory Use of New Approach Methods
Alice Krebs
, Barbara M. A. van Vugt-Lussenburg
, Tanja Waldmann
, François Dominique Busquet
, Xenia Dolde
, Anna-Katharina Holzer
, Jaffar Kisitu
, Giorgia Pallocca
, Costanza Rovida
, Marcel Leist
· 2020