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Epigenetic Changes and Disturbed Neural Development in a Human Embryonic Stem Cell-based Model Relating to the Fetal Valproate Syndrome
Nina Balmer
, Matthias Weng
, Bastian Zimmer
· 2012
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A Human Stem Cell-derived Test System for Agents Modifying Neuronal N-methyl-D-aspartate-type Glutamate Receptor Ca2+-signalling
Stefanie Klima
, Markus Brüll
, Anna-Sophie Spreng
, Ilinca Suciu
, Tjalda Falt
, Jens C. Schwamborn
, Tanja Waldmann
, Christiaan Karreman
, Marcel Leist
· 2021
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Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants
Lisa Hoelting
, Stefanie Klima
, Christiaan Karreman
, Marianna Grinberg
, Johannes Meisig
, Margit Henry
, Tamara Rotshteyn
, Jörg Rahnenführer
, Tanja Waldmann
, Marcel Leist
· 2016
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Recommendation on Test Readiness Criteria for New Approach Methods in Toxicology: Exemplified for Developmental Neurotoxicity
Anna K. Bal-Price
, Helena T. Hogberg
, Kevin M. Crofton
, Mardas Daneshian
, Rex E. FitzGerald
, Ellen Fritsche
, Tuula Heinonen
, Stefanie Klima
, Tanja Waldmann
, Marcel Leist
· 2018
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Extensive Transcriptional Regulation of Chromatin Modifiers During Human Neurodevelopment
Matthias Weng
, Bastian Zimmer
, Dominik Pöltl
· 2012
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Human Embryonic Stem Cell-derived Test Systems for Developmental Neurotoxicity: A Transcriptomics Approach
Anne-Kathrin Krug
, Raivo Kolde
, John Gaspar
· 2013
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The EU-ToxRisk Method Documentation, Data Processing and Chemical Testing Pipeline for the Regulatory Use of New Approach Methods
Alice Krebs
, Barbara M. A. van Vugt-Lussenburg
, Tanja Waldmann
, François Dominique Busquet
, Xenia Dolde
, Anna-Katharina Holzer
, Jaffar Kisitu
, Giorgia Pallocca
, Costanza Rovida
, Marcel Leist
· 2020
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Template for the Description of Cell-based Toxicological Test Methods to Allow Evaluation and Regulatory Use of the Data
Alice Krebs
, Tanja Waldmann
, Costanza Rovida
, Giorgia Pallocca
, Thomas Hartung
, Florian Gantner
, Thomas Exner
, Daniel R. Dietrich
, François Dominique Busquet
, Marcel Leist
· 2019
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Major Changes of Cell Function and Toxicant Sensitivity in Cultured Cells Undergoing Mild, Quasi-natural Genetic Drift
Simon Gutbier
, Patrick May
, Sylvie Berthelot
, Abhimanyu Krishna
, Timo Trefzer
, Mehri Behbehani
, Ljudmila Efremova
, Johannes Delp
, Gerhard Gstraunthaler
, Tanja Waldmann
, Marcel Leist
· 2018
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Combination of Multiple Neural Crest Migration Assays to Identify Environmental Toxicants from a Proof-of-concept Chemical Library
Johanna Nyffeler
, Xenia Dolde
, Alice Krebs
, Kevin Pinto-Gil
, Manuel Pastor
, Mamta Behl
, Tanja Waldmann
, Marcel Leist
· 2017