BOOKQUE

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Development of a Neurotoxicity Assay that is Tuned to Detect Mitochondrial Toxicants
Johannes Delp , Melina Funke , Franziska Rudolf , Andrea Cediel , Susanne Hougaard Bennekou , Wanda van der Stel , Giada Carta , Paul Jennings , Cosimo Toma , Marcel Leist
· 2019
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Dynamic Metabolic and Transcriptional Responses of Proteasome-Inhibited Neurons
Ilinca Suciu , Johannes Delp , Simon Gutbier , Anna-Katharina Ückert , Anna-Sophie Spreng , Christiaan Karreman , Falk Schreiber , Ivana Celardo , Ivano Amelio , Marcel Leist
· 2023
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A High-throughput Approach to Identify Specific Neurotoxicants/ Developmental Toxicants in Human Neuronal Cell Function Assays
Johannes Delp , Simon Gutbier , Stefanie Klima , Lisa Hölting , Kevin Pinto-Gil , Jui-Hua Hsieh , Michael Aichem , Karsten Klein , Falk Schreiber , Marcel Leist
· 2018
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Mapping the Cellular Response to Electron Transport Chain Inhibitors Reveals Selective Signaling Networks Triggered by Mitochondrial Perturbation
Wanda van der Stel , Huan Yang , Nanette G. Vrijenhoek , Giulia Callegaro , Giada Carta , Johannes Delp , Marcel Leist , Bob van de Water , Erik Hendrik Julius Danen
· 2022
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Functional and Mechanistic Approaches to Improve Neurotoxicity Predictions
Johannes Delp
· 2019
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Shortened Derivatives from Native Antimicrobial Peptide LyeTx I: In Vitro and in Vivo Biological Activity Assessment
Leonardo Lima Fuscaldi , Joaquim Teixeira de Avelar Júnior , Daniel Moreira Dos Santos , Daiane Boff , Vívian Louise Soares de Oliveira , Karla Aparecida Guimarães Gusmão Gomes , Rosana de Carvalho Cruz , Patrícia Luciana de Oliveira , Johannes Delp , Marcel Leist
· 2021
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Pharmacological LRH-1/Nr5a2 Inhibition Limits Pro-inflammatory Cytokine Production in Macrophages and Associated Experimental Hepatitis
Juliane Schwaderer , Truong San Phan , Astrid Glöckner , Johannes Delp , Marcel Leist , Thomas Brunner , M. Eugenia Delgado
· 2020
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New Approach Methods Supporting Read-across: Two Neurotoxicity AOP-based IATA Case Studies
Wanda Van der Stel , Giada Carta , Julie Eakins , Johannes Delp , Ilinca Suciu , Anna Forsby , Andrea Cediel-Ulloa , Marcel Leist , Susanne Hougaard Bennekou , Bob van de Water
· 2021
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Major Changes of Cell Function and Toxicant Sensitivity in Cultured Cells Undergoing Mild, Quasi-natural Genetic Drift
Simon Gutbier , Patrick May , Sylvie Berthelot , Abhimanyu Krishna , Timo Trefzer , Mehri Behbehani , Ljudmila Efremova , Johannes Delp , Gerhard Gstraunthaler , Tanja Waldmann , Marcel Leist
· 2018
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Prevention of Neuronal Apoptosis by Astrocytes Through Thiol-mediated Stress Response Modulation and Accelerated Recovery from Proteotoxic Stress
Simon Gutbier , Anna-Sophie Spreng , Johannes Delp , Stefan Schildknecht , Christiaan Karreman , Ilinca Suciu , Thomas Brunner , Marcus Groettrup , Marcel Leist
· 2018