Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Prologue: Families -- "The missing science of heredity" 1865-1935 -- "In the sum of the parts, there are only the parts" 1930-1970 -- "The dreams of geneticists" 1970-2001 -- "The proper study of mankind is man" 1970-2005 -- Through the looking glass 2001-2015 -- Post-genome 2015- ... -- Epilogue: Bheda, Abheda

A magnificent, beautifully written biography of cancer - from its first documented appearances thousands of years ago through the epic battles to cure, control and conquer it to a radical new understanding of its essence. In The Emperor of All Maladies, Siddhartha Mukherjee, doctor, researcher and award-winning science writer, examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years.The story of cancer is a story of human ingenuity, resilience and perseverance, but also of hubris, arrogance and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out `war against cancer'. Mukherjee recounts centuries of discoveries, setbacks, victories and deaths, told through the eyes of predecessors and peers, training their wits against an infinitely resourceful adversary.From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteeth-century recipient of primitive radiation and chemotherapy and Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through toxic, bruising, and draining regimes to survive and to increase the store of human knowledge.Riveting and magesterial, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments and a brilliant new perspective on the way doctors, scientists, philosophers and lay people have observed and understood the human body for millennia.

"Presenting revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, the author draws on his own experience as a researcher, doctor, and prolific reader to explore how the discovery of cells created a new kind of medicine based on the therapeutic manipulation of cells"--

Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

Apa yang membentuk diri, kehidupan, sifat, bahkan nasib manusia? Pencarian selama ribuan tahun menunjukkan adanya unsur pembawa pewarisan sifat antargenerasi makhluk hidup, termasuk manusia. Ternyata unsur itu bukan sesuatu yang gaib, bukan bintang-bintang jauh, melainkan ada dalam diri kita, berwujud fi sik sehingga bisa ditemukan upaya sains: gen, instruksi pembentukan dan pengoperasian tubuh yang tertulis di molekul asam deoksiribonukleat (DNA) di seluruh sel kita. Sejarah gen, mulai dari gagasan awal, perumusan prinsip, penemuan struktur, sampai rekayasanya, disampaikan melalui kisah para pencarinya, dari Aristoteles dan Mendel, Watson dan Crick, hingga saintis abad ke-21. Dan sesudah mengetahui mengenai gen dan pengaruhnya bagi hidup, kepribadian, dan nasib, kita menghadapi tantangan sekaligus peluang: apa jadinya jika kita bisa mengetahui kecenderungan fi sik bawaan gen? Bisakah kehidupan diperbaiki dengan rekayasa gen? Siapkah kita memegang kemampuan mengubah nasib genetis umat manusia?

I Granta #7 om service gör nya och etablerade författare en översyn av ett ord som väcker känslor och skapar debatt. Lars Berge ringer till bredbandssupporten och granskar servicesamhället, debutanten Julia Stenroth skildrar det monotona arbetet på en svinfarm och Dimitris Alevras berättar om en nybliven nattklubbschef omgiven av spritfläckar och minnen. Ida Therén ritar upp June Mansfield Millers liv och Susanna Alakoski beskriver sjukvårdsupplysningens tjänster. Åke Smedberg skriver om komplexa relationer i en trött småstad och så undersöker Elin Cullhed maktbalansen i ett familjehem. Ur internationella Granta kommer bland annat en berättelse om ett butiksbiträde som gör allt för sin kund, en novell om en dubbelarbetande mamma och en historia om dödshjälp. Svenska Granta är del av ett internationellt nätverk med engelskspråkiga Granta som nav. Tidskriften grundades av studenter i Cambridge i slutet av 1800-talet. År 1979 fick den sin nuvarande form som en arena för nyskriven skönlitteratur och litterära reportage. I dag finns Grantaredaktioner i ett tiotal länder världen över, från Kina till Brasilien. www.albertbonniersforlag.se/granta Twitter/Instagram: GrantaSweden

The book provides the whole horizon of process engineering and plant design from concept phase through the execution to commissioning of the plant in the real practice. Providing a complete industrial perspective, the book: Covers the guidelines and standards followed in the industry and how engineering documents are generated using these standards Describes Hazardous Area Classification, Relief System Design, Revamp Engineering, Interaction with Other Disciplines, and Pre-commissioning and Commissioning Contains several illustrated practical examples, which clarify the fundamentals to a raw chemical engineer Includes description of a complete chemical project from concept to commissioning Treating the topic from the perspective of an industrial employee with extensive experience in process engineering and plant design, it aims to aid chemical and plant engineers to deal with decision making processes on strategic level, management tasks and leading functions beside the technical know-how.

National Book Critics Circle Award—2017 Nonfiction Finalist “Nothing less than a tour de force—a heady amalgam of science, history, a little bit of anthropology and plenty of nuanced, captivating storytelling.”—The New York Times Book Review, Editor’s Choice A National Geographic Best Book of 2017 In our unique genomes, every one of us carries the story of our species—births, deaths, disease, war, famine, migration, and a lot of sex. But those stories have always been locked away—until now. Who are our ancestors? Where did they come from? Geneticists have suddenly become historians, and the hard evidence in our DNA has blown the lid off what we thought we knew. Acclaimed science writer Adam Rutherford explains exactly how genomics is completely rewriting the human story—from 100,000 years ago to the present.