Michael Knauth stellt die Rolle der Medien für die Öffentlichkeit dar, erläutert technische Grundlagen von Internet und digitalem Fernsehen, analysiert Marktbedingungen, Wettbewerbsstrategien und Angebotskonzepte und zeigt regulative Ansätze für die Zugangssicherung auf.

Aktuelles auf höchstem Niveau auch bei kniffligen Fällen auf Fragen zu Technik, Differenzialdiagnose und Geräteeinstellung Alle Abbildungen mit sehr hoher Detailgenauigkeit Mehr als und Grafiken Sie diskutieren das Krankheitsbild auf einer Augenhöhe mit dem Kliniker Der sichere Weg zu.

- Der Wegweiser zu einer hochqualifizierten Diagnostik und Therapie: alles zu den Diagnoseverfahren bei den einzelnen Verschlussarten sowie zu den verschiedenen Therapiemethoden - Detaillierte Empfehlungen zur Durchführung der interventionellen Behandlun

Abstract: Background Flow diverters (FD) are used regularly for the endovascular treatment of unruptured intracranial aneurysms. We aimed to assess the safety and effectiveness of the Derivo embolization device (DED) with respect to long-term clinical and angiographic outcomes. Methods A prospective multicenter trial was conducted at 12 centers. Patients presenting with modified Rankin Score (mRS) of 0-1, treated for unruptured intracranial aneurysms with DED were eligible. Primary endpoint was the mRS assessed at 18 months with major morbidity defined as mRS 3-5. Satisfactory angiographic occlusion was defined as 3+4 on the Kamran scale. Results Between July 2014 and February 2018, 119 patients were enrolled. Twenty-three patients were excluded. Ninety-six patients, 71 (74%) female, mean age 54±12.0 years, were included in the analysis. Mean aneurysm size was 14.2±16.9 mm. The mean number of devices implanted per patient was 1.2 (range 1-3). Clinical follow-up at 18 months was available in 90 (94%) patients, resulting in a mean follow-up period of 14.8±5.2 months. At last available follow-up of 96 enrolled patients, 91 (95%) remained mRS 0-1. The major morbidity rate (mRS 3-5) was 3.1% (3/96), major stroke rate was 4.2% (4/96), and mortality was 0%. Follow-up angiographies were available in 89 (93%) patients at a median of 12.4±5.84 months with a core laboratory adjudicated satisfactory aneurysm occlusion in 89% (79/89). Conclusion Our results suggest that DED is a safe and effective treatment for unruptured aneurysms with high rates of satisfactory occlusion and comparably low rates of permanent neurological morbidity and mortality. Trial registration DRKS00006103