This book describes the current status of the very rapidly developing field of high-field MR and examines the possibilities, challenges, and limitations of this fascinating technology. In the initial chapters, the basic technological background is explained in a non-technical way so as to promote understanding of the issues and concepts and avoid overwhelming the reader with excessive detail. Safety issues, methods, and contrast are then carefully considered. The final part of the book examines the diverse applications of high-field MR imaging in radiology, neuroscience, oncology, and other fields, with the aid of numerous high-quality illustrations. All chapters are written by leading experts who have taken great care to illustrate the potential and progress of the field in an informative and accessible manner. The book will appeal to all with a potential interest in the application of high-field MR imaging, including radiologists, neuroscientists, and oncologists.

The International Society for the Study of Individual Differences unites researchers, teachers, and students interested in all areas of individual differences (e.g., gender, temperament, personality, intelligence) and their assessment in human and animal research.The Society's aim is to investigate the major dimensions of individual differences in the context of experimental, physiological, pharmacological, clinical, medical, genetical, statistical, and social psychology, as well as to seek the determinants, causes and concomitants of individual differences, using concepts derived from these disciplines.This volume contains abstracts of the latest research presented at the Society's 13th biennial meeting held in Giessen, Germany, and provides an excellent source of up-to-date research information for all those interested in individual differences in a wide variety of fields.

Menschen wie Dietrich Bonhoeffer, Martin Luther King oder Malala Yousafzai sind als mutige, furchtlose Persönlichkeiten und Vorbilder bekannt geworden. Ein starker Charakter hat diese unheimliche Strahlkraft und kann dem Leben einen Sinn und Erfüllung geben. Doch wie kann man den eigenen Charakter besser kennen lernen und stärken? Jürgen Hennig, ein führender Experte auf dem Gebiet der Persönlichkeitsentwicklung, lädt in diesem Buch dazu ein, die individuellen Charakterstärken kennenzulernen und aufblühen zu lassen. Anhand von 24 verschiedenen Eigenschaften aus den Bereichen: Weisheit und Wissen, Mut, Liebe und Menschlichkeit, Gerechtigkeit, Mäßigung, Spiritualität und Transzendenz. Ein wegweisender Ratgeber, der dabei hilft, die eigene Persönlichkeit zu entfalten und seine Lebensziele langfristig zu verwirklichen.

Wer ungewöhnliche und fantasievolle Geschichten liebt, wird an diesem Buch seine Freude haben. Erdan trifft die Frau seiner Träume, doch die verführerische Ardak ist auch eine Wölfin. Er folgt ihrem Ruf in die Wildnis. Die Sorge eines Autofahrers um einen verletzten Fuchs wird mit einem Wunder belohnt: Die Große Mutter erscheint dem Tierfreund in der Nacht. Ein merkwürdig aussehender Mann setzt sich zu Gerd ans Lagerfeuer. Ein Landstreicher, ein Bettler? Ein Neandertaler! Diese Begegnung verändert Gerds Leben für immer. Es folgen weitere kurze Erzählungen bis hin zur berührenden Weihnachtsgeschichte, in der Herbert, ein Obdachloser, das Fest allein begeht.

Abstract: Multiple sites within Germany operate human MRI systems with magnetic fields either at 7 Tesla or 9.4 Tesla. In 2013, these sites formed a network to facilitate and harmonize the research being conducted at the different sites and make this technology available to a larger community of researchers and clinicians not only within Germany, but also worldwide. The German Ultrahigh Field Imaging (GUFI) network has defined a strategic goal to establish a 14 Tesla whole-body human MRI system as a national research resource in Germany as the next progression in magnetic field strength. This paper summarizes the history of this initiative, the current status, the motivation for pursuing MR imaging and spectroscopy at such a high magnetic field strength, and the technical and funding challenges involved. It focuses on the scientific and science policy process from the perspective in Germany, and is not intended to be a comprehensive systematic review of the benefits and technical challenges of higher field strengths

Abstract: Purpose Cardiovascular diseases remain the number one death cause worldwide. Preclinical 4D flow phase contrast magnetic resonance imaging can provide substantial insights in the analysis of aortic pathophysiologies in various animal models. These insights may allow a better understanding of pathophysiologies, therapy monitoring, and can possibly be translated to humans. This study provides a framework to acquire the velocity field within the aortic arch. It analyses important flow values at different locations within the aortic arch. Imaging parameters with high temporal and spatial resolution are provided, that still allow combining this time-consuming method with other necessary imaging-protocols. Methods A new setup was established where a prospectively gated 4D phase contrast sequence is combined with a highly sensitive cryogenic coil on a preclinical magnetic resonance scanner. The sequence was redesigned to maintain a close to steady state condition of the longitudinal magnetization and hence to overcome steady state artifacts. Imaging parameters were optimized to provide high spatial and temporal resolution. Pathline visualizations were generated from the acquired velocity data in order to display complex flow patterns. Results Our setup allows data acquisition with at least two times the rate than that of previous publications based on Cartesian encoding, at an improved image quality. The "steady state" sequence reduces observed artifacts and provides uniform image intensity over the heart cycle. This made possible quantification of blood speed and wall shear stress (WSS) within the aorta and its branches. The highest velocities were observed in the ascending aorta with 137.5 ± 8 cm/s. Peak velocity values in the Brachiocephalic trunk were 57 ± 12 cm/s. Quantification showed that the peak flow occurs around 20 ms post R-wave in the ascending aorta. The highest mean axial wall shear stress was observed in the analysis plane between the left common carotid artery (LCCA) and the left subclavian artery. A stable image quality allows visualizing complex flow patterns by means of streamlines and for the first time, to the best of our knowledge, pathline visualizations from 4D flow MRI in mice. Conclusion The described setup allows analyzing pathophysiologies in mouse models of cardiovascular diseases in the aorta and its branches with better image quality and higher spatial and temporal resolution than previous Cartesian publications. Pathlines provide an advanced analysis of complex flow patterns in the murine aorta. An imaging protocol is provided that offers the possibility to acquire the aortic arch at sufficiently high resolution in less than one hour. This allows the combination of the flow assessment with other multifunctional imaging protocols